Darren Fletcher and Paul Scholes were missing from Manchester United's travelling party for their Champions League Group H clash with Braga.
The pair did not make the trip as Sir Alex Ferguson's team set off for a game in Group H which can book their place in the knockout stages with a victory.
Following wins over Galatasaray, Cluj and, at Old Trafford, Braga, United will progress to the last 16 with two games to spare if they pick up another three points on Wednesday night.
But Braga's recent record against English teams in Portugal is impressive and so Ferguson will know it will not be a straightforward night.
Braga did not concede a goal in posting victories over Birmingham City, Liverpool, Arsenal and Portsmouth during the past five years.
And so coach Jose Peseiro will have the perfect motivation with which to supply his players as they look ahead to hosting United for the first time in their history.
Braga currently have three points in the group to leave them sitting third between second-placed Cluj and Galatasaray in what looks like a three-way fight for the runners-up spot.
Douglao (thigh) returned to action at the weekend after missing Braga's last three matches in all competitions.
But Paulo Vinicius, Ismaily, Paulo Cesar, Carlao and Djamal were all sidelined through injury.