Frank Schleck has failed a drugs test at the Tour de France, the International Cycling Union (UCI) has announced.
The Luxembourger, who finished third in last year's race, failed a test for the diuretic Xipamide on 14 July.
He has not been suspended from the race and has the right to request the analysis of his urine sample.
Schleck, the older brother of 2010 winner Andy, is racing with the RadioShack team run by Johan Bruyneel.
A team spokesman had no immediate comment.
"Earlier today, the UCI advised Frank Schleck of an adverse analytical finding (presence of the diuretic Xipamide) in the urine sample collected from him at an in-competition test at the Tour de France on 14 July 2012," the UCI said in a statement.
He 12th in this year's Tour de France, nine minutes and 45 seconds behind leader Bradley Wiggins.
The diuretic is classified as a specified substance and does not require a provisional suspension.
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