Munster and Ulster do battle in an all-Irish Heineken Cup quarter-final at Thomond Park - and both sides have much to prove.
The hosts have a fantastic record in Europe's premier club competition but go into the knockout contest off the back of two defeats in their last three outings.
They also lost the last time the two teams met - Ulster came out on top 33-17 at Ravenhill in RaboDirect PRO12 action earlier in the campaign.
However, that impressive December win came when Tony McGahan's outfit were without their first-choice Ireland internationals, so the visitors will want to prove that it was no one-off.
Reaction
Munster boss McGahan has reacted to last week's loss to Leinster by making seven changes to his side, handing first Heineken Cup
starts to hooker Mike Sherry and flank Tommy O'Donnell.
starts to hooker Mike Sherry and flank Tommy O'Donnell.
In the backs, there are two changes; Denis Hurley, who is back from injury, and Conor Murray replace Johne Murphy and Tomas O'Leary, the latter duo having to make do with a place on the bench.
Up front, Wian du Preez starts his seventh consecutive Heineken Cup game and Donnacha Ryan and Paul O'Connell return from injury. Peter O'Mahony switches from seven to six and O'Donnell is preferred to David Wallace.
Ulster have made just one change to the starting team that registered a 45-7 victory over Aironi last Friday - Dan Tuohy returns to partner Johann Muller.
There's also an alteration to their list of replacements, Nevin Spence being drafted in at the expense of Ian Whitten.
Munster: 15 Felix Jones, 14 Denis Hurley, 13 Keith Earls, 12 Lifeimi Mafi, 11 Simon Zebo, 10 Ronan O'Gara, 9 Conor Murray, 8 James Coughlan, 7 Tommy O'Donnell, 6 Peter O'Mahony, 5 Paul O'Connell, 4 Donnacha Ryan, 3 BJ Botha, 2 Mike Sherry, 1 Wian du Preez.
Replacements: 16 Damien Varley, 17 Marcus Horan, 18 Stephen Archer, 19 Donncha O'Callaghan, 20 David Wallace, 21 Tomas O'Leary, 22 Ian Keatley, 23 Johne Murphy.
Ulster: 15 Stefan Terblanche, 14 Andrew Trimble, 13 Darren Cave, 12 Paddy Wallace, 11 Craig Gilroy, 10 Ian Humphreys, 9 Ruan Pienaar, 8 Pedrie Wannenburg, 7 Chris Henry, 6 Stephen Ferris, 5 Dan Tuohy, 4 Johann Muller (capt), 3 John Afoa, 2 Rory Best, 1 Tom Court.
Replacements: 16 Nigel Brady, 17 Paddy McAllister, 18 Adam Macklin, 19 Lewis Stevenson, 20 Willie Faloon, 21 Paul Marshall, 22 Nevin Spence, 23 Adam D'Arcy.