David Warner fell 20 runs short of a double century as Australia dominated day two of the third Test and put themselves in a position to wrap up the series with India.
The opener, who was unbeaten on 104 overnight after scoring the equal fourth-fastest Test hundred in history, took his score to 180 before his 159-ball innings came to an end.
Umesh Yadav's maiden five-wicket haul restricted Australia to 369 but it still gave them a first innings lead of 208.
And India had stumbled to 88-4 at the close with three days still to play in Perth.
The hosts, who lead the four match series 2-0, had looked on course for far more than their eventual total after Warner and Ed Cowan took their opening stand to 214 before Yadav squeezed a delivery through Cowan's defences to bowl him for a Test-best 74.
Yadav quickly sent Shaun Marsh and Ricky Ponting on their way, the latter falling to a searing off-cutter that uprooted his middle stump.
Warner, who was dropped on 126, was unable to reproduce his onslaught from the opening day, when he reached triple figures in 69 balls, with a blow to his elbow restricting his normal flow.
He did offer glimpses of his hard hitting, smashing Ishant Sharma back over his head for six.
But after lunch until he attempted another lusty blow over mid-on off the same bowler and was caught in the deep, his 180 including 20 fours and five sixes.
That prompted a clatter of wickets as Australia lost their last six men for 79 runs but any thoughts of an Indian fightback were soon silenced by the home attack.
Openers Gautam Gambhir and Virender Sehwag were both undone by pace and bounce, caught behind off Mitchell Starc and Peter Siddle respectively, in consecutive overs.
Starc then grabbed the biggest scalp of his three-Test career when he trapped Sachin Tendulkar lbw before the out-of-sorts VVS Laxman offered yet another edge, this time off Ben Hilfenhaus, to Shaun Marsh without scoring.
Rahul Dravid and Virat Kohli held out for the final hour of the day but with India trailing by 120 runs with three days still to play a heavy defeat looks inevitable.